Home Categories Pharmaceutical intermediates 2,4-Diamino-6-hydroxypyrimidine
A3530312

2,4-Diamino-6-hydroxypyrimidine , >98.0%(HPLC) , 56-06-4

CAS NO.:56-06-4

Empirical Formula: C4H6N4O

Molecular Weight: 126.12

MDL number: MFCD00006098

EINECS: 200-254-4

Pack Size Price Stock Quantity
5g RMB24.00 In Stock
25G RMB31.20 In Stock
100G RMB75.20 In Stock
500G RMB262.40 In Stock
2.5kg RMB1183.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 285-286 °C (dec.) (lit.)
Boiling point: 234.22°C (rough estimate)
Density  1.3659 (rough estimate)
refractive index  1.7990 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka 10.61±0.50(Predicted)
form  Fine Crystalline Powder
color  White to cream
Sensitive  Light Sensitive
Merck  14,2981
BRN  125006
InChIKey SWELIMKTDYHAOY-UHFFFAOYSA-N

Description and Uses

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
Hazard Note  Irritant
TSCA  Yes
HS Code  29335995

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