Dinoprost , ≥99% , 38562-01-5

Synonym(s):
(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt;PGF_2α−Tris;Prostaglandin F_2α tris salt

CAS NO.：38562-01-5

Empirical Formula: C24H45NO8

Molecular Weight: 475.62

MDL number: MFCD00077863

EINECS: 254-002-3

PRODUCT Properties

• Melting point: 100-101°
• storage temp.: -20°C
• solubility: H₂O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.
• form: powder
• color: white
• Merck: 13,7970
• BRN: 4087514
• Stability: Hygroscopic
• InChIKey: IYGXEHDCSOYNKY-RZHHZEQLSA-N

Description and Uses

Dinoprost tromethamine is a synthetic analogue of prostaglandin. F2α is an autocrine hormone present in many mammalian tissues. It is used to cause luteolysis in the cow, sow and mare. It is given as a single injection by im or sc routes, the recommended dosage rate is 25 mg cow; 10 mg sow and 5 mg mare. It is rapidly absorbed from the injection site. It has an extremely short half life of only a few minutes, it is almost completely cleared following one or two passages through the liver and/or lungs.

One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both prostaglandins are biosynthesized from the same precursors and that PGF2 is the synthetic reduction product of PGE2. Phospholipase A2 (PLA2) is a key enzyme for biosynthesis of PGF2α. Oxytocic; abortifacient.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360FD
• Precautionary statements: P202-P264-P270-P280-P301+P312-P308+P313
• Hazard Codes: T
• Risk Statements: 60-22
• Safety Statements: 53-45
• WGK Germany: 3
• RTECS: UK8025000
• F: 8-10
• HS Code: 2937500000