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A3387412

Diisopropylamine dichloroacetate , 95% , 660-27-5

CAS NO.:660-27-5

Empirical Formula: C8H17Cl2NO2

Molecular Weight: 230.132

MDL number: MFCD00868288

EINECS: 211-538-2

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
250MG RMB23.20 In Stock
5G RMB27.20 In Stock
25G RMB56.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 119-121°
RTECS  AG6475000
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  Crystalline Powder
color  White
Merck  14,3197
Stability: Hygroscopic
InChI InChI=1S/C6H15N.C2H2Cl2O2/c1-5(2)7-6(3)4;3-1(4)2(5)6/h5-7H,1-4H3;1H,(H,5,6)
InChIKey ILKBHIBYKSHTKQ-UHFFFAOYSA-N
SMILES C(O)(=O)C(Cl)Cl.CC(NC(C)C)C
CAS DataBase Reference 660-27-5
EPA Substance Registry System Acetic acid, dichloro-, compd. with N-(1-methylethyl)-2-propanamine (1:1) (660-27-5)

Description and Uses

Diisopropylammonium dichloroacetate is a hepatoprotective drug that improves the energy metabolism of hepatocytes, promotes the regeneration of injured hepatocytes, increases the rate of tissue cell respiration and oxygen respiration, and reduces the accumulation of fat in the liver. It is mainly used clinically for the treatment of fatty liver, intrahepatic cholestasis, and general liver dysfunction. It is also used in the treatment of acute and chronic hepatitis, hepatomegaly, and early cirrhosis.

Diisopropylammonium dichloroacetate (DIPA) is known to produce a significant and prolonged hypoglycemic effect in alloxan-diabetic but not in normal rats.
Diisopropylamine 2,2-Dichloroacetate is used in the treatment of antituberculosis drugs-induced liver injury.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
TSCA  Yes
HS Code  2921199990
Toxicity LD50 orally in mice: 1700 mg/kg (Kraushaar)

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