Desogestrel , ≥98.0%(HPLC) , 54024-22-5

Synonym(s):
13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol;Desogestrel

CAS NO.：54024-22-5

Empirical Formula: C22H30O

Molecular Weight: 310.47

MDL number: MFCD00869346

EINECS: 258-929-4

PRODUCT Properties

• Melting point: 109-110°C
• alpha: D20 +55° (chloroform)
• Boiling point: 390.62°C (rough estimate)
• Density: 1.0169 (rough estimate)
• refractive index: 1.5100 (estimate)
• storage temp.: -20°C Freezer
• solubility: Practically insoluble in water, very soluble in methanol, freely soluble in anhydrous ethanol and in methylene chloride.
• form: Solid
• pka: 13.07±0.40(Predicted)
• color: White to Almost white
• Merck: 14,2926

Description and Uses

Desogestrel is a synthetic progestogen. It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8⁺ T cells in a dose-dependent manner. Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.

A progestogen with low androgenic potency

Safety

• Symbol(GHS): GHS08,GHS09
• Signal word: Danger
• Hazard statements: H360FD-H410
• Precautionary statements: P202-P273-P280-P308+P313-P391-P405
• Safety Statements: 24/25
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: JF7975000
• HS Code: 29372390
• Hazardous Substances Data: 54024-22-5(Hazardous Substances Data)