A3369112
3,4-Dichlorophenylacetonitrile , 98% , 3218-49-3
Synonym(s):
3,4-Dichlorobenzyl cyanide
CAS NO.：3218-49-3
Empirical Formula: C8H5Cl2N
Molecular Weight: 186.04
MDL number: MFCD00001909
EINECS: 221-743-9
| Pack Size | Price | Stock | Quantity |
| 5g | RMB24.00 | In Stock |
|
| 25G | RMB36.00 | In Stock |
|
| 100G | RMB121.60 | In Stock |
|
| 250g | RMB294.40 | In Stock |
|
| 500g | RMB480.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 39-42 °C (lit.) |
| Boiling point: | 170 °C/12 mmHg (lit.) |
| Density | 1.4274 (rough estimate) |
| refractive index | 1.5690 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| color | White |
| BRN | 638749 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 3218-49-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 3,4-Dichlorophenylacetonitrile(3218-49-3) |
Description and Uses
3,4-Dichlorophenylacetonitrile was used in the synthesis of:
- SR 48968, a potent, competitive and selective non-peptide antagonist of the neurokinin A (NK2) receptor
- tachykinin NK3 receptor antagonist SR 142801, (R)-N-[ 1-[3-[ 1-benzoyl-3-(3,4-dichlororphenyl)-3-piperidinyl]propyyl]-4-phenyl-4-piperidinyl-N-methyl acetamide
- MDL 105,212, a non-peptide tachykinin receptor antagonist
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-37/39-36/37/39 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29269095 |
