4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester , ≥97% , 146998-31-4

Synonym(s):
4-(Dimethylamino)azobenzene-4′-carboxylic acid N-succinimidyl ester;DABCYL-N-succinimidyl ester;Dabcyl-OSu;N-(4-[4Æ-(Dimethylamino)phenylazo]benzoyloxy)succinimide

CAS NO.：146998-31-4

Empirical Formula: C19H18N4O4

Molecular Weight: 366.37

MDL number: MFCD00467415

PRODUCT Properties

• Melting point: 242 °C(dec.)
• Boiling point: 550.7±60.0 °C(Predicted)
• Density: 1.30±0.1 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: Soluble in DMSO.
• form: powder to crystal
• pka: 3.28±0.10(Predicted)
• color: Light yellow to Amber to Dark green
• Sensitive: Moisture Sensitive
• InChIKey: IBOVDNBDQHYNJI-QZQOTICOSA-N
• CAS DataBase Reference: 146998-31-4

Description and Uses

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
• Safety Statements: 24/25
• RIDADR: 3234
• WGK Germany: 3
• F: 10-21
• HS Code: 29280000