1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) , ≥97% , 200880-42-8

CAS NO.：200880-42-8

Empirical Formula: C81H159Na2O16P

Molecular Weight: 1466.07

MDL number: MFCD00077290

PRODUCT Properties

• storage temp.: -20°C
• solubility: Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
• form: Solid
• color: White to Off-White
• Stability: Hygroscopic

Description and Uses

DSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.

1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.

Safety

• WGK Germany: 3