Home Categories API Dirithromycin
A3325412

Dirithromycin , ≥97% , 62013-04-1

Synonym(s):
[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxy)ethylidene]oxy]erthromycin; LY-237216

CAS NO.:62013-04-1

Empirical Formula: C42H78N2O14

Molecular Weight: 835.07

MDL number: MFCD00865041

EINECS: 624-080-7

Pack Size Price Stock Quantity
1G RMB111.20 In Stock
5G RMB391.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 186-189° (dec) (Counter)
Boiling point: 871.8±65.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  Very slightly soluble in water, very soluble in methanol and in methylene chloride
pka 9.0 in 66% aq dimethyl fluoride
form  solid
color  white to off-white

Description and Uses

Dirithromycin, an orally active oxazine derivative of erythromycin, is a secondgeneration macrolide antibiotic. It was first introduced in Spain for the treatment of respiratory tract, skin and soft tissue infections. It is safe and effective in treating acute bronchitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, pharyngitis, and tonsillitis. Dirithromycin has been reported to have a similar antimicrobial spectrum and potency to erythromycin. However, compared to other macrolide antibiotics, dirithromycin has improved oral bioavailability, higher tissue permeability and longer duration of action. The once-daily therapy regiment is advantageous in terms of patient compliance and is a good alternative for patients who are unable to take penicillin.

antihypertensive

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280
Hazard Codes  Xn,Xi
Risk Statements  42/43-36/37/38
Safety Statements  36-26
WGK Germany  3
HS Code  29419000
Toxicity LD50 in mice (g/kg): >1 s.c.; >1 orally (Maier)

RELATED PRODUCTS