2,3-Dichloroquinoxaline , 98% , 2213-63-0
CAS NO.:2213-63-0
Empirical Formula: C8H4Cl2N2
Molecular Weight: 199.04
MDL number: MFCD00006720
EINECS: 218-667-3
Pack Size | Price | Stock | Quantity |
5G | RMB52.80 | In Stock |
|
25G | RMB151.20 | In Stock |
|
100G | RMB468.80 | In Stock |
|
500g | RMB1146.40 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 152-154 °C (lit.) |
Boiling point: | 325.69°C (rough estimate) |
Density | 1.4994 (rough estimate) |
refractive index | 1.6400 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
Water Solubility | Insoluble in water |
solubility | soluble in Chloroform |
form | Needles |
pka | -4.78±0.48(Predicted) |
color | Off-white to light brown |
BRN | 126076 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | SPSSDDOTEZKOOV-UHFFFAOYSA-N |
CAS DataBase Reference | 2213-63-0(CAS DataBase Reference) |
EPA Substance Registry System | 2,3-Dichloroquinoxaline (2213-63-0) |
Description and Uses
2,3-Dichloroquinoxaline (DCQX) can be used as a substrate for nucleophilic aromatic substitution (SNAr) reactions and is a versatile building block for the synthesis of many quinoxaline derivatives. 2,3-Dichloroquinoxaline reacts with 6-aminothiouracil in ethanol/TEA to form 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one. It reacts with cholest-5-en-3-one semicarbazone/thiosemicarbazone to form steriodal cholest-5-en-3-oxazolo and thiazoloquinoxaline.
2,3-Dichloroquinoxaline was used in the synthesis of mono and 2,3-disubstituted quinoxalines. It was used in solid phase synthesis of HPLC chiral stationary phase containing the N,N′-dialkyl-2,3-diaminoquinoxaline group as a linking structure.
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301-H315-H319-H335 |
Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 |
Hazard Codes | T |
Risk Statements | 25-36/37/38 |
Safety Statements | 26-36/37/39-45-37/39-28A |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | VD1720000 |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29339900 |
Toxicity | mouse,LD50,intravenous,5600ug/kg (5.6mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03256, |