Home Categories 2,3-Dichloroquinoxaline
A3297312

2,3-Dichloroquinoxaline , 98% , 2213-63-0

CAS NO.:2213-63-0

Empirical Formula: C8H4Cl2N2

Molecular Weight: 199.04

MDL number: MFCD00006720

EINECS: 218-667-3

Pack Size Price Stock Quantity
5G RMB52.80 In Stock
25G RMB151.20 In Stock
100G RMB468.80 In Stock
500g RMB1146.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 152-154 °C (lit.)
Boiling point: 325.69°C (rough estimate)
Density  1.4994 (rough estimate)
refractive index  1.6400 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
Water Solubility  Insoluble in water
solubility  soluble in Chloroform
form  Needles
pka -4.78±0.48(Predicted)
color  Off-white to light brown
BRN  126076
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey SPSSDDOTEZKOOV-UHFFFAOYSA-N
CAS DataBase Reference 2213-63-0(CAS DataBase Reference)
EPA Substance Registry System 2,3-Dichloroquinoxaline (2213-63-0)

Description and Uses

2,3-Dichloroquinoxaline (DCQX) can be used as a substrate for nucleophilic aromatic substitution (SNAr) reactions and is a versatile building block for the synthesis of many quinoxaline derivatives. 2,3-Dichloroquinoxaline reacts with 6-aminothiouracil in ethanol/TEA to form 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one. It reacts with cholest-5-en-3-one semicarbazone/thiosemicarbazone to form steriodal cholest-5-en-3-oxazolo and thiazoloquinoxaline.

2,3-Dichloroquinoxaline was used in the synthesis of mono and 2,3-disubstituted quinoxalines. It was used in solid phase synthesis of HPLC chiral stationary phase containing the N,N′-dialkyl-2,3-diaminoquinoxaline group as a linking structure.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  26-36/37/39-45-37/39-28A
RIDADR  2811
WGK Germany  3
RTECS  VD1720000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29339900
Toxicity mouse,LD50,intravenous,5600ug/kg (5.6mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03256,

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