Home Categories Organic Chemistry Diethyl (bromodifluoromethyl)phosphonate
A3274712

Diethyl (bromodifluoromethyl)phosphonate , 97% , 65094-22-6

Synonym(s):
(Bromodifluoromethyl)phosphonic acid diethyl ester

CAS NO.:65094-22-6

Empirical Formula: C5H10BrF2O3P

Molecular Weight: 267.01

MDL number: MFCD00069118

Pack Size Price Stock Quantity
1G RMB24.00 In Stock
5G RMB64.00 In Stock
25G RMB255.20 In Stock
100g RMB758.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 40-41 °C/0.05 mmHg (lit.)
Density  1.503 g/mL at 25 °C (lit.)
refractive index  n20/D 1.417(lit.)
Flash point: >230 °F
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Chloroform, Ethyl Acetate
form  liquid
Specific Gravity 1.503
color  colorless
Water Solubility  Not miscible or difficult to mix in water.
BRN  1944045
CAS DataBase Reference 65094-22-6(CAS DataBase Reference)

Description and Uses

Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  21/22-36/38-38-36
Safety Statements  26-36/37/39-60-37-23
RIDADR  3278
WGK Germany  3
Hazard Note  Irritant
TSCA  No
HazardClass  IRRITANT, IRRITANT-HARMFUL
PackingGroup  III
HS Code  29319090

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