Cis-1,2-dichloroethylene in methanol , 0.985mg/ml, matrix: methanol , 156-59-2

Synonym(s):
cis-1,2-DCE;cis-1,2-Dichloroethylene;cis-Acetylene dichloride

CAS NO.：156-59-2

Empirical Formula: C2H2Cl2

Molecular Weight: 96.94

MDL number: MFCD00000925

EINECS: 205-859-7

PRODUCT Properties

• Melting point: -80 °C (lit.)
• Boiling point: 60 °C (lit.)
• Density: 1.284 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.449(lit.)
• Flash point: 43 °F
• storage temp.: 2-8°C
• solubility: soluble in Chloroform
• form: Liquid
• color: Clear colorless
• Water Solubility: 3.5g/L(25 ºC)
• Merck: 14,92
• BRN: 1071208
• Dielectric constant: 9.1999999999999993
• Stability: Volatile

Description and Uses

cis-1,2-Dichloroethylene (cis-1,2-DCE) is generally used in the preparation of various enediynes for Bergman cyclization. Applications include the synthesis of:

• 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines to prepare corresponding substituted carbazoles.
• (Z)-1-aryl-3-henen-1,5-diynes to obtain the corresponding aryl substituted benzotriazoles.

It is used as a linker to synthesize boron-dipyrromethene (BODIPY)-based photosensitizer for photodynamic therapy (PDT). cis-1,2-DCE can also be used as a precursor to synthesize intermediates of sporolide B.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H302+H332-H315-H412
• Precautionary statements: P210-P233-P273-P301+P312-P303+P361+P353-P304+P340+P312
• Hazard Codes: F,Xn,T
• Risk Statements: 11-20-52/53-39/23/24/25-23/24/25
• Safety Statements: 7-16-29-61-45-36/37
• RIDADR: UN 1150 3/PG 2
• OEB: A
• OEL: TWA: 200.0 ppm; 790.0 mg/m3
• WGK Germany: 2
• RTECS: KV9420000
• F: 1-8-10
• HazardClass: 3.1
• PackingGroup: II
• HS Code: 29032990
• Toxicity: cat,LCLo,inhalation,20gm/m3/6H (20000mg/m3),BEHAVIORAL: GENERAL ANESTHETICBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.