A3250112
1,3-Dioxlane , Waterless grade, 99.8%, containing 75ppMBHT stabilizers , 646-06-0
Synonym(s):
1,3-Dioxacyclopentane, Formaldehyde ethylene acetal, Ethylene glycol methylene ether;1,3-Dioxolane;Ethylene glycol methylene ether;Formaldehyde ethylene acetal
CAS NO.:646-06-0
Empirical Formula: C3H6O2
Molecular Weight: 74.08
MDL number: MFCD00003207
EINECS: 211-463-5
Update time: 2022-07-08
PRODUCT Properties
Melting point: | -95 °C (lit.) |
Boiling point: | 75-76 °C/1.013 hPa |
Density | 1.06 g/mL at 25 °C (lit.) |
vapor density | 2.6 (vs air) |
vapor pressure | 70 mm Hg ( 20 °C) |
refractive index | n |
Flash point: | 35 °F |
storage temp. | Store at <= 20°C. |
solubility | 1000g/l soluble |
form | Liquid |
color | White to off-white |
explosive limit | 2.1-20.5%(V) |
Water Solubility | SOLUBLE |
BRN | 102453 |
Exposure limits | ACGIH: TWA 20 ppm |
Stability: | Below 4°C |
InChIKey | WNXJIVFYUVYPPR-UHFFFAOYSA-N |
LogP | -0.37 at 20℃ |
CAS DataBase Reference | 646-06-0(CAS DataBase Reference) |
NIST Chemistry Reference | 1,3-Dioxolane(646-06-0) |
EPA Substance Registry System | 1,3-Dioxolane (646-06-0) |
Description and Uses
Dioxolane is a water-white liquid. Molecularweight= 74.09; Boiling point = 74℃; Flash point = 2℃(oc). Hazard Identification (based on NFPA-704 M RatingSystem): Health 2, Flammability 4, Reactivity 2. Soluble in water.
1,3-Dioxolane is an intermediate for the preparation of Acyclovir (A192400). Also, 1,3-Dioxolane is used in the synthesis of new Vandetanib (V097100) analogs.
Safety
Symbol(GHS) | GHS02,GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H225-H319-H360 |
Precautionary statements | P201-P210-P305+P351+P338-P308+P313 |
Hazard Codes | F |
Risk Statements | 11 |
Safety Statements | 16 |
RIDADR | UN 1166 3/PG 2 |
WGK Germany | 1 |
RTECS | JH6760000 |
Autoignition Temperature | 525 °F |
TSCA | Yes |
HazardClass | 3 |
PackingGroup | II |
HS Code | 29329970 |
Hazardous Substances Data | 646-06-0(Hazardous Substances Data) |
Toxicity | LD50 orally in Rabbit: 3000 mg/kg LD50 dermal Rabbit 9074 mg/kg |