Home Categories Chemical Reagents Dichloroacetonitrile
A3196712

Dichloroacetonitrile , 98% , 3018-12-0

Synonym(s):
2,2-Dichloroacetonitrile;Dichloromethyl cyanide

CAS NO.:3018-12-0

Empirical Formula: C2HCl2N

Molecular Weight: 109.94

MDL number: MFCD00040886

EINECS: 221-159-4

Update time: 2022-07-08

PRODUCT Properties

Boiling point: 110-112 °C(lit.)
Density  1.369 g/mL at 25 °C(lit.)
refractive index  n20/D 1.44(lit.)
Flash point: 96 °F
storage temp.  0-6°C
solubility  soluble in Methanol
Specific Gravity 1.37
color  Colorless to Light yellow to Light orange
BRN  1739029
Exposure limits NIOSH: IDLH 25 mg/m3
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.

Description and Uses

Dichloroacetonitrile can be used as a reactant to prepare:

  • Chiral α, α-dichloro-β-aminonitriles via Pd-catalyzed enantioselective Mannich-type reaction with imines.
  • α, α-dialkyl-substituted nitriles by an alkylation reaction with trialkylboranes in the presence of phenoxide base as a base.
  • Halogenated pyridines via copper-catalyzed reaction with methacrolein.
  • α,α-dichloro-β-hydroxy nitriles by condensation reaction with aldehydes and ketones in the presence of an alkoxide base.
  • Selenium heterocycle derivatives via Diels–Alder cyclization with selenoaldehydes.
  • Dichloroacetonitrile can also be used to develop an efficient method for the extraction and determination of common volatile halogenated disinfection by-products using the static headspace technique coupled with gas chromatography-mass spectrometry.

Safety

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H302-H314
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  C
Risk Statements  10-22-34
Safety Statements  26-36/37/39-45-25-16
RIDADR  UN 2920 8/PG 2
WGK Germany  3
RTECS  AL8465000
9-19
HazardClass  3
PackingGroup  II
HS Code  29269090

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