3,3-Diethoxypropionic Acid Ethyl Ester , 95% , 10601-80-6

Synonym(s):
Malonaldehydic acid ethyl ester diethylacetal

CAS NO.：10601-80-6

Empirical Formula: C9H18O4

Molecular Weight: 190.24

MDL number: MFCD00009865

EINECS: 234-223-1

PRODUCT Properties

• Melting point: 200-202 °C
• Boiling point: 92-93 °C/13 mmHg (lit.)
• Density: 0.978 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.411(lit.)
• Flash point: 184 °F
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Liquid
• color: Clear colorless
• BRN: 1772110
• Stability: Hygroscopic
• InChI: InChI=1S/C9H18O4/c1-4-11-8(10)7-9(12-5-2)13-6-3/h9H,4-7H2,1-3H3
• InChIKey: SIALOQYKFQEKOG-UHFFFAOYSA-N
• SMILES: C(OCC)(=O)CC(OCC)OCC
• LogP: 2.260 (est)
• CAS DataBase Reference: 10601-80-6(CAS DataBase Reference)

Description and Uses

Ethyl 3,3-diethoxypropionate is an organic compound that is synthesized from the reaction of diethyl malonate and chloroacetic acid in the presence of a base catalyst. This product has been shown to be an effective inhibitor of mitochondrial cytochrome c oxidase in vitro studies. Ethyl 3,3-diethoxypropionate also has been found to inhibit quinoline derivatives, such as erythromycin and tetracycline, which are involved in bacterial DNA synthesis. Furthermore, this product inhibits β-unsaturated aldehydes and allylation.

Ethyl 3,3-diethoxypropionate participates in the Yb(OTf)3 catalyzed synthesis of dihydropyridines (DHPs).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227
• Precautionary statements: P210e-P280a-P370+P378a-P501a-P210-P280-P370+P378-P403+P235-P501
• Safety Statements: 23-24/25
• WGK Germany: 3
• F: 10-21
• HS Code: 29189900