Dextran , Mw,20000 , 9004-54-0

Synonym(s):
Dextran;DEXTRAN 40;DEXTRAN 70;Dextran Ladder

CAS NO.：9004-54-0

Empirical Formula: C17H32O10

Molecular Weight: 396.43

MDL number: MFCD00130935

EINECS: 232-677-5

PRODUCT Properties

• Melting point: 483 °C (decomp)
• alpha: 198 º
• refractive index: 185 ° (C=6, H2O)
• storage temp.: 2-8°C
• solubility: H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow
• form: Solid
• color: White to slightly off-white
• PH: 2 - 10
• optical activity: +208 to +233 (formaldehyde)
• Water Solubility: Soluble in water, dimethyl sulfoxide, ethylene glycol and glycerol.
• Merck: 14,2948
• Stability: Stable. Keep dry. Incompatible with strong oxidizing agents.
• LogP: -4.259 (est)
• EPA Substance Registry System: Dextran (9004-54-0)

Description and Uses

Dextrans are glucose polymers produced by bacteria linked in an α-1,6 chain and having an α-1,3 or α-1,4 branch about every fifth residue. The specific positioning of the branching varies by the bacterium producing it. The molecular weights of these chains generally are 40 or 70 kDa (dextran-40 and dextran-70, respectively), and the compounds work via an osmotic gradient similar to the colloids and hypertonic crystalloid solutions.
Dextrans have a longer intravascular residence time than albumin, which limits interstitial edema. As with the crystalloids and other colloids, the dextrans have no oxygen-carrying capacity. Furthermore, because they are bacterial products, the dextrans have the potential to be potent antigens and induce anaphylaxis.

antiinflammatory veterinary drug

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H303
• Precautionary statements: P270-P301+P312-P403-P501c
• Hazard Codes: Xn,Xi
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-37/39-36-26
• WGK Germany: 2
• RTECS: HH9230000
• F: 3
• TSCA: Yes
• HS Code: 39139000
• Toxicity: LD50 oral in rat: > 3gm/kg