Home Categories Organic Chemistry 2,6-Difluorophenylboronic acid
A3102312

2,6-Difluorophenylboronic acid , 98% , 162101-25-9

CAS NO.:162101-25-9

Empirical Formula: C6H5BF2O2

Molecular Weight: 157.91

MDL number: MFCD01318987

EINECS: 627-874-1

Pack Size Price Stock Quantity
1G RMB28.80 In Stock
5G RMB72.80 In Stock
25G RMB234.40 In Stock
100g RMB876.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 147-149 °C (lit.)
Boiling point: 260.1±50.0 °C(Predicted)
Density  1.35±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Soluble in methanol.
form  solid
pka 8.12±0.58(Predicted)
color  White to Almost white
BRN  8545931
InChIKey DBZAICSEFBVFHL-UHFFFAOYSA-N

Description and Uses

2,6-Difluorophenylboronic acid can be used:

  • As a substrate in the model reaction of Suzuki–Miyaura coupling with?4-chloro-3-methylanisole.
  • To prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors.
  • To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29163990

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