Home Categories Pharmaceutical intermediates 5-Chloro-2,4,6-trifluoropyrimidine
A2890912

5-Chloro-2,4,6-trifluoropyrimidine , 95% , 697-83-6

CAS NO.:697-83-6

Empirical Formula: C4ClF3N2

Molecular Weight: 168.5

MDL number: MFCD00191933

EINECS: 211-807-4

Pack Size Price Stock Quantity
25G RMB719.20 In Stock
100G RMB2088.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 116 °C(lit.)
Density  1.626 g/mL at 25 °C(lit.)
refractive index  n20/D 1.439(lit.)
Flash point: >230 °F
pka -9.30±0.39(Predicted)
form  Liquid
color  Clear colorless
Specific Gravity 1.626
BRN  610168
CAS DataBase Reference 697-83-6(CAS DataBase Reference)
EPA Substance Registry System Pyrimidine, 5-chloro-2,4,6-trifluoro- (697-83-6)

Description and Uses

5-Chloro-2,4,6-trifluoropyrimidine can be used as a starting material to synthesize:

  • 4-azido-5-chloro-2,6-difluoro-pyrimidine by azidation reaction with sodium azide.
  • 5-chloro triphenoxy pyrimidine by reacting with tetraphenoxysilane in the presence of tetra butyl ammonium fluoride (TBAF).
  • 5-chloro-2,6-difluoropyrimidin-4-amine, and 5-chloro-4,6-difluoropyrimidin-2-amine (9:1 ratio) by reacting with ammonia.
  • 5-Chloro-N,N -diethyl-2,6-dipyrimidin-4-amine, by treating with diethylamine and DIPEA.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT, MOISTURE SENSITIVE
HS Code  29335990

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