Isothiazolinones , mixtureofCMIandMI,2.0-2.5%inwater,PH：2.0-5.0

Synonym(s):
5-chloro-2-methyl-2h-isothiazolin-3-one/2-methyl-2h-isothiazol-3-one

CAS NO.：

Empirical Formula: C4H4ClNOS

Molecular Weight: 149.6

MDL number: MFCD00792550

EINECS: 247-500-7

PRODUCT Properties

• Melting point: 42-45?C
• Boiling point: 109.7°C
• Density: 1.25 (14% aq.)
• refractive index: n20/D 1.378
• storage temp.: Refrigerator
• solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
• form: Liquid
• pka: -4.06±0.40(Predicted)
• Stability: Stable. Incompatible with strong oxidizing agents.
• LogP: 0.240 (est)
• CAS DataBase Reference: 26172-55-4(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
• EPA Substance Registry System: 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)

Description and Uses

Methy1chloro-isothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI. It is irritant and sensitizer.

A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H317-H319-H412
• Precautionary statements: P261-P264-P273-P280-P302+P352-P305+P351+P338
• Hazard Codes: C,N,T,Xn
• Risk Statements: 34-43-50-20/21/22-50/53-23/24/25-42/43
• Safety Statements: 26-36/37/39-45-60-61-24-28-36/37-23
• RIDADR: UN 1760 8/PG 2
• WGK Germany: 1
• RTECS: NX8156850
• HazardClass: 8
• PackingGroup: III
• HS Code: 3808929090
• Hazardous Substances Data: 26172-55-4(Hazardous Substances Data)