Clemizole hydrochloride , 98%(HPLC) , 1163-36-6

Synonym(s):
1-(p-Chlorobenzyl)-2-(1-pyrrolidinylmethyl)benzimidazole hydrochloride;1-(p-Chlorobenzyl)-2-pyrrolidylmethylenebenzimidazole hydrochloride;1-[(4-Chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-1H-benzimidazole hydrochloride;CID 2782 hydrochloride;NSC 46261 hydrochloride

CAS NO.：1163-36-6

Empirical Formula: C19H21Cl2N3

Molecular Weight: 362.3

MDL number: MFCD00051435

EINECS: 214-605-4

PRODUCT Properties

• Melting point: 239-241°
• storage temp.: Inert atmosphere,2-8°C
• solubility: H2O: soluble2mg/mL, clear (warmed)
• form: powder
• color: white to beige
• Water Solubility: 16.84mg/L at 25℃
• Merck: 14,2346
• InChIKey: DNFMJYXRIMLMBZ-UHFFFAOYSA-N
• LogP: 1.99
• CAS DataBase Reference: 1163-36-6(CAS DataBase Reference)

Description and Uses

Clemizole Hydrochloride inhibits Hepatitis C RNA replication in cell culture through the suppression of the binding between the nonstructural protein 4B and the viral RNA genome with little toxicity for the host cell. Clemizole Hydrochloride is also a potent inhibitor of transient receptor potential channel TRPC5.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: DD6730000
• HS Code: 2933.99.8290