2-Chloro-4-iodoaniline , >98.0%(GC)(T) , 42016-93-3
CAS NO.：42016-93-3
Empirical Formula: C6H5ClIN
Molecular Weight: 253.47
MDL number: MFCD00025298
EINECS: 628-520-9
| Pack Size | Price | Stock | Quantity |
| 1G | RMB30.40 | In Stock |
|
| 5G | RMB64.80 | In Stock |
|
| 25G | RMB208.00 | In Stock |
|
| 100G | RMB688.80 | In Stock |
|
| 500g | RMB2744.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 70-73 °C (lit.) |
| Boiling point: | 281.7±25.0 °C(Predicted) |
| Density | 1.9011 (estimate) |
| storage temp. | Refrigerated. |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 1.86±0.10(Predicted) |
| form | powder to crystal |
| color | Light yellow to Brown to Dark green |
| Sensitive | Light Sensitive |
| BRN | 2081106 |
Description and Uses
2-Chloro-4-iodoaniline is a chemical compound that has been synthesized for use as a reagent. It has been used to produce the drug cobimetinib, which is used in the treatment of cancer. 2-Chloro-4-iodoaniline can be prepared by reaction of magnesium with 2-chloroacetaldehyde and nitric acid. This reagent is also useful for preparing Grignard reagents. 2-Chloro-4-iodoaniline can be used to deaminate ketones, nitrates, and chlorides in high yield. 2,4,6-trichlorophenylalanine is an organic compound that contains all three functional groups: a chloride group, a ketone group, and an amino group. The chlorinated carbon atom of the chloride group makes it a good nucleophile and electrophile.
Safety
| Symbol(GHS) |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H315-H318-H335 |
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | T,N,Xi,Xn |
| Risk Statements | 25-37/38-41-51/53-36/37/38-20/21/22 |
| Safety Statements | 26-36/37-45-60-61-36/37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214200 |
