4-Chloro-2-nitrophenol , 98% , 89-64-5
CAS NO.：89-64-5
Empirical Formula: C6H4ClNO3
Molecular Weight: 173.55
MDL number: MFCD00007113
EINECS: 201-927-5
PRODUCT Properties
| Melting point: | 85-87 °C(lit.) |
| Boiling point: | 242.5±20.0 °C(Predicted) |
| Density | 1.4914 (rough estimate) |
| refractive index | 1.5810 (estimate) |
| solubility | dioxane: soluble0.5g/5mL, clear, faintly yellow to yellow |
| pka | pK1: 6.48 (25°C) |
| form | powder to crystal |
| color | Light yellow to Yellow to Orange |
| BRN | 2048031 |
Description and Uses
Reduction of 4-Chloro-2-nitrophenol gives 2-amino-4- chlorophenol [95-85-2], and chlorination yields 2,4-dichloro-6-nitrophenol [609-89-2], which is reduced to 2-amino-4,6-dichlorophenol [527-62-8]. These substituted aminophenols are members of a large class of diazo components used for hydroxyazo dyes, which are important for wool and polyamide when converted to their chromium complexes. For the amine derived from the methyl ether of 4-Chloro-2-nitrophenol, 4- chloro-o-anisidine [93-50-5], the preferred route is methoxylation of 2,5-dichloronitrobenzene followed by reduction. 2-amino-4-chlorophenol reacts with phosgene to give 5- chlorobenzoxolinone which nitrates to the 6-nitro compound; the latter undergoes alkaline hydrolysis to 2-amino-4- chloro-5-nitrophenol.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36-36/37/39 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29089990 |
