Carbendazim , 97% , 10605-21-7

Synonym(s):
Carbendazim;BCM;Methyl 2-benzimidazolecarbamate;Methyl benzimidazol-2-ylcarbamate;TNFRSF17

CAS NO.：10605-21-7

Empirical Formula: C9H9N3O2

Molecular Weight: 191.19

MDL number: MFCD00055390

EINECS: 234-232-0

PRODUCT Properties

• Melting point: >300 °C (lit.)
• Boiling point: 326.92°C (rough estimate)
• Density: 1.4500
• vapor pressure: 1.5 x 10^-4 Pa (25 °C)
• refractive index: 1.6500 (estimate)
• Flash point: 11 °C
• storage temp.: -20°C
• solubility: pyridine: soluble1%, clear, very faintly brownish-yellow
• pka: 4.48(at 25℃)
• form: Solid
• color: White to off-white
• Water Solubility: <0.1 g/100 mL at 21 ºC
• Merck: 13,1799
• BRN: 649044
• InChIKey: TWFZGCMQGLPBSX-UHFFFAOYSA-N
• LogP: 1.4-1.5 at 25℃ and pH5-9

Description and Uses

Carbendazim is the degradation product and active ingredient of the carbamate fungicide benomyl. Carbendazim (100 μM) disrupts the growth of S. cerevisiae by inhibiting microtubule polymerization. It impairs meiosis and steroidogenesis in an ex vivo rat model of seminiferous tubules and increases prostate weight in rats when administered at a dose of 100 mg/kg but does not affect other testosterone-dependent or estrogen-dependent tissues.

Carbendazim is the most widely used active ingredient in the benzimidazole class of fungicides. It is a systemic fungicide with both protective and curative activities against a wide range of fungal diseases, especially caused by most Ascomycetes spp. and some Basidiomycetes and Deuteromycetes spp. in a wide variety of crop and ornamental uses.

Safety

• Symbol(GHS): GHS08,GHS09
• Signal word: Danger
• Hazard statements: H340-H360FD-H410
• Precautionary statements: P202-P273-P280-P308+P313-P391-P405
• Hazard Codes: T,N,F,Xn
• Risk Statements: 46-60-61-50/53-39/23/24/25-23/24/25-11-52/53
• Safety Statements: 53-45-60-61-36/37-16
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• RTECS: DD6500000
• HS Code: 29339900
• Toxicity: LD50 oral in rabbit: 8160mg/kg