Home Categories Chemical Reagents 2-Chloro-6-methylaniline
A2514212

2-Chloro-6-methylaniline , ≥98.0%(GC) , 87-63-8

Synonym(s):
2-Amino-3-chlorotoluene;6-Chloro-o-toluidine

CAS NO.:87-63-8

Empirical Formula: C7H8ClN

Molecular Weight: 141.6

MDL number: MFCD00007679

EINECS: 201-759-2

Pack Size Price Stock Quantity
1G RMB31.20 In Stock
5G RMB36.80 In Stock
25G RMB141.60 In Stock
100g RMB424.00 In Stock
500G RMB1988.00 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 10-12 °C(lit.)
Boiling point: 215 °C(lit.)
Density  1.152 g/mL at 25 °C(lit.)
refractive index  n20/D 1.576(lit.)
Flash point: 210 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly)
pka 2.51±0.10(Predicted)
form  Oil
color  Clear Colourless to Pale Purple
Water Solubility  Immiscible
BRN  774624
InChIKey WFNLHDJJZSJARK-UHFFFAOYSA-N

Description and Uses

2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.

2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.

Safety

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H341-H373-H410
Precautionary statements  P201-P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39
RIDADR  UN 3429 6.1/PG 3
WGK Germany  3
RTECS  XU5100000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29214300

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