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A2475612

Clarithromycin , ≥98% , 81103-11-9

Synonym(s):
6-O-methyl erythromycin;CLM

CAS NO.:81103-11-9

Empirical Formula: C38H69NO13

Molecular Weight: 747.95

MDL number: MFCD00865140

EINECS: 1806241-263-5

Pack Size Price Stock Quantity
1G RMB39.20 In Stock
5G RMB80.80 In Stock
25G RMB221.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 217-220°C
Boiling point: 86℃
alpha  D24 -90.4° (c = 1 in CHCl3)
Density  1.1334 (rough estimate)
refractive index  -92 ° (C=1, CHCl3)
Flash point: >110°(230°F)
storage temp.  -20°C
solubility  Soluble in DMSO
pka pKa 8.99(H2O t=25.0 I=0.167) (Uncertain)
form  powder
color  colorless to faint yellow
Water Solubility  99.48mg/L(20 ºC)
Merck  14,2339
BCS Class 4
Stability: Store in Freezer
InChIKey AGOYDEPGAOXOCK-KCBOHYOISA-N

Description and Uses

Clarithromycin is an acid stable macrolide antibiotic indicated for use in the treatment of skin, urinary and respiratory tract infections. Compared to erythromycin, clarithromycin exhibits the same in vitro activity against conventional pathogens, but is better tolerated by generating less gastrointestinal problems.

A macrolide antibiotic and protein synthesis inhibitor

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-60
WGK Germany  3
RTECS  KF4997000
HS Code  29419000
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 2740, 2700, 3470, 2700 orally, 1030, 850, 669, 753 i.p., >5000 all s.c. (Abe)

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