A2453612
Clidinium bromide , Analysis standard , 3485-62-9
Synonym(s):
3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane bromide;3-Hydroxy-1-methylquinuclidinium bromide benzilate
CAS NO.：3485-62-9
Empirical Formula: C22H26BrNO3
Molecular Weight: 432.35
MDL number: MFCD00078996
EINECS: 222-471-3
| Pack Size | Price | Stock | Quantity |
| 1G | RMB637.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 240-241°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 3485-62-9(CAS DataBase Reference) |
Description and Uses
Clidinium is a gastrointestinal muscarinic receptor antagonist (Ki = 3 nM against [3H]quinuclidinyl benzilate binding in rat colonic enterocytes). Administration of clidinium, at a dose of 1 mg/kg, slows intestinal transit and induces constipation in mice. This clidinium-induced constipation induces serum hyperammonemia and decreases clonic, myoclonic, and tonic seizure thresholds in a murine pentylenetetrazole-induced epilepsy model.
An anticholinergic. Used as an antispasmodic.
