4-Chloro-N-methylpyridine-2-carboxamide , 97% , 220000-87-3

CAS NO.：220000-87-3

Empirical Formula: C7H7ClN2O

Molecular Weight: 170.6

MDL number: MFCD02185921

EINECS: 606-888-1

PRODUCT Properties

• Melting point: 41-43°C
• Boiling point: 317.8±27.0 °C(Predicted)
• Density: 1.264±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
• form: Solid
• pka: 13.41±0.46(Predicted)
• color: Off-White to Light Yellow

Description and Uses

4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.

4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xn
• Risk Statements: 22-36
• Safety Statements: 26
• HS Code: 2933399990