Home Categories Pharmaceutical intermediates 4-Chloro-N-methylpyridine-2-carboxamide
A2446412

4-Chloro-N-methylpyridine-2-carboxamide , 97% , 220000-87-3

CAS NO.:220000-87-3

Empirical Formula: C7H7ClN2O

Molecular Weight: 170.6

MDL number: MFCD02185921

EINECS: 606-888-1

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB52.80 In Stock
25G RMB158.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 41-43°C
Boiling point: 317.8±27.0 °C(Predicted)
Density  1.264±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form  Solid
pka 13.41±0.46(Predicted)
color  Off-White to Light Yellow
CAS DataBase Reference 220000-87-3(CAS DataBase Reference)

Description and Uses

4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.

4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
HS Code  2933399990

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