Home Categories Natural Products Corylifolin
A2443212

Corylifolin , Analysis of standard products, ≥98.0% , 19879-32-4

Synonym(s):
(2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;4′,7-Dihydroxy 6-(3-methyl 2-butenyl)flavanone;Corylifolin

CAS NO.:19879-32-4

Empirical Formula: C20H20O4

Molecular Weight: 324.37

MDL number:

Pack Size Price Stock Quantity
20MG RMB191.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 558.3±50.0 °C(Predicted)
Density  1.244
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  ≤20mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
form  crystalline solid
pka 8.27±0.40(Predicted)
color  White

Description and Uses

Bavachin is a flavonoid first isolated from seeds of P. corylifolia. It is a phytoestrogen that activates the estrogen receptors ERα and ERβ (EC50s = 320 and 680 nM, respectively). Through this action, bavachin stimulates osteoblast proliferation and differentiation and prevents bone loss following ovariectomy in rats. Bavachin less potently inhibits acyl-coenzyme A:cholesterol acyltransferase (IC50 = 86 μM).

Bavachin has therapeutic potential for type 2 diabetes by activating insulin signaling pathways. Also, it has anabolic and potent anticatabolic biological effects on chondrocytes. Strong inhibitor of human UDP-glucuronosyltransferase (UGT1A1)

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312

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