Chloromethyl pivalate , 99% , 18997-19-8

Synonym(s):
Pivaloyloxymethyl chloride;POM-Cl

CAS NO.：18997-19-8

Empirical Formula: C6H11ClO2

Molecular Weight: 150.6

MDL number: MFCD00000884

EINECS: 242-735-1

PRODUCT Properties

• Melting point: <-40°C
• Boiling point: 146-148 °C (lit.)
• Density: 1.045 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.417(lit.)
• Flash point: 104 °F
• storage temp.: Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Sparingly)
• form: Liquid
• Specific Gravity: 1.038
• color: Clear colorless to slightly yellow
• Water Solubility: Miscible with most organic solvents. Immiscible with water.
• BRN: 1560838
• InChIKey: GGRHYQCXXYLUTL-UHFFFAOYSA-N
• CAS DataBase Reference: 18997-19-8(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2,2-dimethyl-, chloromethyl ester(18997-19-8)
• EPA Substance Registry System: Propanoic acid, 2,2-dimethyl-, chloromethyl ester (18997-19-8)

Description and Uses

Chloromethyl pivalate was used in the synthesis of pivaloyloxy methyl ester of ofloxacin as prodrug. It was used as the reagent during the synthesis of an isoindoline-annulated, tricyclic sultam library via microwave-assisted, continuous-flow organic synthesis.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Warning
• Hazard statements: H226-H302+H312+H332-H315-H319-H335
• Precautionary statements: P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 10-20/21/22-36/37/38
• Safety Statements: 16-26-36-41-36/37/39
• RIDADR: UN 3272 3/PG 3
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• HS Code: 29159000