Chymostatin , ≥95% , 9076-44-2

Synonym(s):
[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-α-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal;Chymostatin;Chymostatin - CAS 9076-44-2 - Calbiochem;N-(N_α-Carbonyl-Cpd-X-Phe-al)-Phe (Cpd = capreomycidine) (capreomycidine = [S,S]-α-(2-Iminohexahydro-4-pyrimidyl)glycine)

CAS NO.：9076-44-2

Empirical Formula: C92H121N21O18

Molecular Weight: 1809.08

MDL number: MFCD00071059

EINECS: 618-642-0

PRODUCT Properties

• Melting point: 205 °C
• storage temp.: -20°C
• solubility: DMSO: 10 mM Stock solutions stable for months at −20 °C.
• form: White to slightly yellow solid or powder
• color: White or off-white
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Description and Uses

Chymostatin is a bioactive peptide of microbial origin that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase (K_i = 9.36 and 13.1 nM, respectively) while less effectively blocking the activity of cathepsins, papain, and leukocyte elastase. It is without effect on trypsin, thrombin, plasmin, pepsin, and kallikrein.

Chymostatin is a specific inhibitor of α-, β-, γ-, and δ-chymotrypsin.

Safety

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: GC3047700
• F: 10-21