A2328712
D-Cycloserine , 98% , 68-41-7
Synonym(s):
(R)-4-Amino-3-isoxazolidone;D -Cycloserine;4-Amino-3-isoxazolidinone
CAS NO.:68-41-7
Empirical Formula: C3H6N2O2
Molecular Weight: 102.09
MDL number: MFCD00005353
EINECS: 200-688-4
Pack Size | Price | Stock | Quantity |
1G | RMB39.20 | In Stock |
|
5G | RMB104.00 | In Stock |
|
25G | RMB395.20 | In Stock |
|
100g | RMB1457.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 147 °C (dec.)(lit.) |
alpha | 111 º (C=5, 2N NaOH) |
Boiling point: | 191.38°C (rough estimate) |
Density | 1.3516 (rough estimate) |
refractive index | 1.5110 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | water: soluble50mg/mL, clear, colorless to light yellow |
form | powder |
pka | pKa 4.5 (Uncertain) |
color | white to off-white |
optical activity | [α]20/D +115.0±5.0°, c = 2% in H2O |
Water Solubility | SOLUBLE |
Sensitive | Air Sensitive |
Merck | 14,2751 |
BRN | 80798 |
BCS Class | 3/1 |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month. |
CAS DataBase Reference | 68-41-7(CAS DataBase Reference) |
NIST Chemistry Reference | Cycloserine(68-41-7) |
Description and Uses
D-Cycloserine (68-41-7) is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors.1?Blocks kainate-induced seizures2?and displays anticonvulsant effects3?in rat models. D-Cycloserine facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices.4?Second-line drug for the treatment of tuberculosis. ?Enhances activity-dependent plasticity in human adults.5
antibacterial (tuberculostatic)
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P271-P261-P280 |
Hazard Codes | Xn |
Risk Statements | 5-20 |
Safety Statements | 38-36/37-24/25 |
WGK Germany | 2 |
RTECS | NY2975000 |
F | 10-23 |
HS Code | 29419090 |
Hazardous Substances Data | 68-41-7(Hazardous Substances Data) |