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A2316512

Capsaicin , ≥95%(HPLC) , 404-86-4

Synonym(s):
[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide;8-Methyl-N-vanillyl-trans-6-nonenamide;Capsaicin

CAS NO.:404-86-4

Empirical Formula: C18H27NO3

Molecular Weight: 305.41

MDL number: MFCD00017259

EINECS: 206-969-8

Pack Size Price Stock Quantity
25MG RMB302.40 In Stock
100MG RMB797.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 62-65 °C(lit.)
Boiling point: 210-220 C
Density  1.1037 (rough estimate)
refractive index  1.5100 (estimate)
FEMA  3404 | CAPSAICIN
Flash point: 113 °C
storage temp.  2-8°C
solubility  H2O: insoluble
form  Off-white solid
pka 9.76±0.20(Predicted)
color  Off-white
Odor mild warm herbal
Odor Type herbal
Water Solubility  insoluble
Merck  14,1768
BRN  2816484
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey YKPUWZUDDOIDPM-SOFGYWHQSA-N
LogP 4.00
CAS DataBase Reference 404-86-4(CAS DataBase Reference)
EPA Substance Registry System Capsaicin (404-86-4)

Description and Uses

Capsaicin has a mild, warm-herbaceous odor and a burning pungent taste (at 10 ppm). It is used in compounded flavors for sauces where the pungent note is desired. This substance is present in several species of Capsicum (Family, Solanaceae). The sensation of pain, accompanied by irritation and inflammation, is due to substance P depletion from sensory (afferent) nerve fibers. These properties are used to study the physiology of pain and the effects as a counterirritant and gastrointestinal stimulant. This substance may be prepared from 3-chloro-2-isopropyltetrahydropyran; biosynthesis from Capsicum frutescens; separation form cis-capsaicin, pelargonic acid vanilamide, and dihydrocapsaicin, reaction of capsaicin.

analgesic (topical), depletes Substance P, neurotoxic

Safety

Symbol(GHS) 
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H315-H317-H318-H334-H335
Precautionary statements  P280-P301+P310+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  T,T+
Risk Statements  25-37/38-41-42/43-36/37/38
Safety Statements  22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  RA8530000
10-21
HazardClass  6.1(a)
PackingGroup  II
HS Code  29399990
Hazardous Substances Data 404-86-4(Hazardous Substances Data)
Toxicity LD50 oral in mouse: 47200ug/kg

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