A2314712
4-Hydroxyphenylboronic acid , 97% , 71597-85-8
Synonym(s):
(p-Hydroxyphenyl)boronic acid;p-hydroxy-benzeneboronic acid;4-Hydroxybenzeneboronic acid;4-Hydroxyphenylboronic acid
CAS NO.：71597-85-8
Empirical Formula: C6H7BO3
Molecular Weight: 137.93
MDL number: MFCD01074628
EINECS: 615-307-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB28.00 | In Stock |
|
| 5G | RMB62.40 | In Stock |
|
| 25G | RMB194.40 | In Stock |
|
| 100G | RMB668.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >230 °C (lit.) |
| Boiling point: | 351.4±44.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Acetonitrile, DMSO, Methanol |
| form | Powder |
| pka | 9.09±0.10(Predicted) |
| color | Off-white to light brown |
| Water Solubility | 25 g/L |
| BRN | 2963491 |
| InChIKey | COIQUVGFTILYGA-UHFFFAOYSA-N |
| CAS DataBase Reference | 71597-85-8(CAS DataBase Reference) |
Description and Uses
4-Hydroxyphenylboronic acid can be used as a reactant in:
- Suzuki-Miyaura coupling and Stille coupling reactions.
- Palladium-catalyzed aminocarbonylation and cross-coupling reactions.
- Suzuki reaction for preparation of bio-supported palladium nanoparticles as phosphine-free catalysts.
- Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles.
It can also be used to prepare/promote:
- PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis inhibitor).
- Rod-like dendronized polymers containing G4 and G5 ester dendrons via macromonomer approach by living ROMP.
- Estrone-derived cyclopamine analogs as Sonic Hedgehog signaling inhibitors for anti-cancer chemotherapeutics.
- Enzymatic inhibitors for the treatment of Gram-negative bacterial infections.
- Oligoarenes by Suzuki-Miyaura palladium-catalyzed cross-coupling.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 |
| Hazard Codes | Xi,C |
| Risk Statements | 36/37/38-34 |
| Safety Statements | 26-36-37/39-45-36/37/39-27 |
| WGK Germany | 3 |
| TSCA | No |
| HS Code | 2931 90 00 |
| HazardClass | IRRITANT |
