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A2309012

α-Chloralose , 98%,betaanomerca15% , 15879-93-3

Synonym(s):
α-Chloralose;1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose;Anhydro-D-glucochloral;Chloralose

CAS NO.:15879-93-3

Empirical Formula: C8H11Cl3O6

Molecular Weight: 309.53

MDL number: MFCD00005542

EINECS: 240-016-7

Update time: 2022-07-08

PRODUCT Properties

Melting point: 178-182 °C
alpha  18 º (c=2, 95% C2H5OH)
Boiling point: 424.33°C (rough estimate)
Density  1.6066 (rough estimate)
vapor pressure  Negligible at room temperature
refractive index  1.5320 (estimate)
solubility  ethanol: 10 mg/mL or yellow-brown, clear to slightly hazy, colorless to faintly yellow
pka 12.89±0.60(Predicted)
form  Solid
color  White to Almost white
optical activity [α]20/D +17±2°, 5 hr, c = 2% in ethanol
Water Solubility  0.44 g/100 mL (15 ºC)
Merck  14,2072
BRN  85418
Stability: Stable. Incompatible with strong oxidizing agents.
LogP 1.020

Description and Uses

Chloralose, (R)-1,2-O-(2,2,2-trichloroethylidene)- α-D-glucofuranose, is a crystalline powder which is soluble in water, fairly soluble in alcohol, diethyl ether, glacial acetic acid, sparingly soluble in chloroform, practically insoluble in petroleum ether.
Chloralose is produced by reaction of glucose with waterfree chloral under heating (21).

It has been employed widely as an animal anesthetic in the laboratory setting. alpha-chloralose is a true anesthetic or an immobilizing agent with sedative-hypnotic properties has important implications. Canada geese (Branta canadensis) and blue geese (Chen caerulescens) were caught with alpha-chloralose, an oral hypnotic administered on bait. Wild turkeys (Meleagris gallopavo) were captured with alpha-chloralose, an oral anesthetic.

Safety

Symbol(GHS) 
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H332-H336-H410
Precautionary statements  P261-P264-P270-P273-P301+P310-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/22-20/21/22
Safety Statements  16-24/25-28-28A-36
RIDADR  3249
WGK Germany  1
RTECS  FM9450000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29400090
Toxicity LD50 orally in mice: 400 mg/kg (Schafer)

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