Cyanoacetic acid , 98% , 372-09-8
Synonym(s):
Cyanoacetic acid;Malonic acid mononitrile
CAS NO.：372-09-8
Empirical Formula: C3H3NO2
Molecular Weight: 85.06
MDL number: MFCD00002677
EINECS: 206-743-9
PRODUCT Properties
| Melting point: | 65 °C |
| Boiling point: | 108 °C0.15 mm Hg(lit.) |
| Density | 1.3676 (rough estimate) |
| vapor pressure | 0.1 mm Hg ( 100 °C) |
| refractive index | 1.3764 (estimate) |
| Flash point: | 226 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble50mg/mL, clear, colorless to very faintly yellow |
| pka | 2.45(at 25℃) |
| form | Adhering Crystalline Solid |
| color | White to light beige |
| PH | 1.6 (50g/l, H2O, 20℃) |
| Water Solubility | 1000 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| Merck | 14,2689 |
| BRN | 506325 |
| Dielectric constant | 33.0（4℃） |
| InChIKey | MLIREBYILWEBDM-UHFFFAOYSA-N |
| LogP | -0.76 |
| CAS DataBase Reference | 372-09-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, cyano-(372-09-8) |
| EPA Substance Registry System | Cyanoacetic acid (372-09-8) |
Description and Uses
Cyanoacetic acid is an organic compound. It is a white, hygroscopic solid. The compound contains two functional groups, a nitrile (C≡N) and a carboxylic acid. It is a precursor to cyanoacrylates, components of adhesives.
Cyanoacetic acid is used in pharmaceutical industry for producing vitamin B6 and caffeine. It is also used in making dyes, agricultural chemicals, and in the synthesis of phenylacetic acid esters. It acts as a precursor cyanoacrylates viz. ethyl cyanoacrylate.
Cyanoacetic acid was used in the synthesis of N-piperidine-cyanacetamide and N-morpholyl-cyanacetamide. It was also used in the preparation of a panchromatic dye for dye-sensitized solar cells.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302+H332-H314 |
| Precautionary statements | P260-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| Hazard Codes | C |
| Risk Statements | 22-31-34-52/53-20/22 |
| Safety Statements | 26-36/37/39-45-61-20 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 2 |
| RTECS | AG3675000 |
| F | 3-10-21 |
| TSCA | Yes |
| HS Code | 2926 90 70 |
| HazardClass | 8 |
| PackingGroup | II |
| Hazardous Substances Data | 372-09-8(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
