Cholesterol , Used for cell culture, 99%(GC) , 57-88-5

Synonym(s):
Cholesterol;Cholesterol from wool fat;Cholesterol, Highly Purified - CAS 57-88-5 - Calbiochem;Cholesterolum;Synthetic cholesterol

CAS NO.：57-88-5

Empirical Formula: C27H46O

Molecular Weight: 386.66

MDL number: MFCD00003646

EINECS: 200-353-2

PRODUCT Properties

• Melting point: 148-150 °C
• Boiling point: 360 °C
• alpha: -36 º (c=2, dioxane)
• Density: 1.06
• refractive index: 1.5250 (estimate)
• Flash point: 250 °C
• storage temp.: -20°C
• solubility: H₂O: 0.002 mg/mL
• form: powder
• pka: 15.03±0.70(Predicted)
• Specific Gravity: 1.067
• color: white
• Odor: wh. or faintly yel. pearly granules or crystals, almost odorless
• Water Solubility: negligible
• Merck: 14,2201
• BRN: 1915888
• Dielectric constant: 2.9（Ambient）
• InChIKey: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• LogP: 9.619 (est)

Description and Uses

Cholesterol is a soft waxy substance that is a steroidal alcohol or sterol. It is the most abundant steroid in the human body and is a component of every cell. Cholesterol is essential to life and most animals and many plants contain this compound. Cholesterol biosynthesis occurs primarily in the liver, but it may be produced in other organs. A number of other substances are synthesized from cholesterol including vitamin D, steroid hormones (including the sex hormones), and bile salts. Cholesterol resides mainly in cell membranes.
Humans produce about 1 gram of cholesterol daily in the liver. Dietary cholesterol is consumed through food. High cholesterol foods are associated with saturated fats and trans-fatty acids (commonly called trans fats). Dietary cholesterol comes from animal products (plants contain minute amounts of cholesterol) such as meats and dairy products.

Cholesterol be used as pharmaceutical intermediates and be used as synthetic materials of liquid crystal polymers.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H319-H331-H336-H351-H361d-H372
• Precautionary statements: P201-P261-P304+P340+P312-P305+P351+P338-P308+P313-P403+P233
• Hazard Codes: Xn,Xi
• Risk Statements: 10-48/20/22-40-38-22-36/37/38-67-36/38-20-63
• Safety Statements: 24/25-22-36/37-36-26
• RIDADR: UN 1170 3/PG 3
• WGK Germany: 1
• RTECS: FZ8400000
• TSCA: Yes
• HS Code: 2906 13 10
• HazardClass: IRRITANT
• Toxicity: Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.