A1543050
OctadecanedioicAcidMono-tert-butylEster , 98% , 843666-40-0
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB129.60 | In Stock |
|
| 1g | RMB388.00 | In Stock |
|
| 5g | RMB1080.80 | In Stock |
|
| 25g | RMB2683.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 68 °C |
| Boiling point: | 470.7±18.0 °C(Predicted) |
| Density | 0.950±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.78±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C22H42O4/c1-22(2,3)26-21(25)19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20(23)24/h4-19H2,1-3H3,(H,23,24) |
| InChIKey | WDUQJXKBWRNMKI-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCC(O)=O |
Description and Uses
Octadecanedioic acid mono-tert-butyl ester is a non-cleavable ADC linker or alkyl chain-based PROTAC linker for the synthesis of antibody-drug couplings (ADCs) and PROTACs.
18-(tert-Butoxy)-18-oxooctadecanoic Acid is a synthetic intermediate used in the preparation of semaglutide. It can be produced by the catalysis of 18-hydroxyoctadecanoic acid by ethyl bromoacetate in the presence of formamide and magnetic trifluoroacetic acid.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405 |
| HS Code | 2917198090 |
