Emetinedihydrochloride , ≥98% , 316-42-7

Synonym(s):
6ʹ,7ʹ,10,11-Tetramethoxyemetan, 2HCl;6′,7′,10,11-Tetramethoxyemetan dihydrochloride;Emetine, Dihydrochloride - CAS 316-42-7 - Calbiochem

CAS NO.：316-42-7

Empirical Formula: C29H42Cl2N2O4

Molecular Weight: 553.56

MDL number: MFCD00135589

EINECS: 206-259-8

Update time: 2022-07-08

PRODUCT Properties

Melting point:	240-250 °C (dec., dry matter)(lit.)
alpha	D +11° (c = 1) to D +21° (c = 8)
storage temp.	2-8°C
solubility	DMSO:55.36(Max Conc. mg/mL);100.0(Max Conc. mM)
form	White solid with a faint yellow cast
Water Solubility	Soluble to 100 mM in water
Merck	14,3559
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents. Light and heat sensitive.
EPA Substance Registry System	Emetine, dihydrochloride (316-42-7)

Description and Uses

Emetine, an alkaloid from ipecac, C29H40O4N2, is a white powder with a very bitter taste. The substance is soluble in alcohol and ether, slightly soluble in water. Emetine darkens upon exposure to light. The compound is derived by extraction from the root of Cephalis ipecacuanha (ipecac). It is also made synthetically. Medically, ipecac is useful as an emetic (induces vomiting) for emergency use in the treatment of drug overdosage and in certain cases of poisoning. Ipecac should not be administered to persons in an unconscious state. It should be noted that emesis is not the proper treatment in all cases of potential poisoning. It should not be induced when such substances as petroleum distillates, strong alkali, acids, or strychnine are ingested.

Safety

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300-H315-H319
Precautionary statements	P264-P270-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes	T+
Risk Statements	28-36/37/38
Safety Statements	26-28-36/37-45
RIDADR	UN 1544 6.1/PG 1
WGK Germany	3
RTECS	JY5250000
F	3-8-10
HazardClass	6.1(a)
PackingGroup	I
Toxicity	LD50 (calculated as base) in mice (mg/kg): 32 s.c.; 30 orally (Child)