2,6-Bis[(3aR,8aS)-(+)-8H-indeno[1,2-d]oxazolin-2-yl)pyridine , ≥94% , 357209-32-6

Synonym(s):
(3aR,3′aR,8aS,8′aS)-2,2′-(2,6-Pyridinediyl)bis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole;(3aR,8aS)-in-pybox

CAS NO.：357209-32-6

Empirical Formula: C25H19N3O2

Molecular Weight: 393.44

MDL number: MFCD09265074

PRODUCT Properties

• Melting point: 284 °C (dec.)
• Boiling point: 633.0±55.0 °C(Predicted)
• Density: 1.50±0.1 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• pka: 4.35±0.20(Predicted)
• optical activity: [α]20/D +386°, c = 1 in methylene chloride(lit.)

Description and Uses

Catalytic ligand used for:

• [3+2] cycloaddition of N-tosyl aziridines with electron-rich alkenes via selective carbon-carbon bond cleavage
• Enantioselective Mukaiyama-aldol reactions
• Enantioselective carbonyl-ene reactions
• Cu(I)-catalyzed asymmetric alkynylation of imino esters with terminal alkynes
• Asymmetric three-component coupling reactions catalyzed by a Cu/pybox complex
• Enantioselective Diels-Alder reaction
• Ni-catalyzed cross-coupling reactions

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29349990