A1443712
Boc-7-Ahp-OH , ≥98.0% , 60142-89-4
Synonym(s):
7-(Boc-amino)enanthic acid;7-(Boc-amino)heptanoic acid;Boc-7-aminoheptanoic acid
Pack Size | Price | Stock | Quantity |
1G | RMB120.80 | In Stock |
|
5G | RMB430.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 56-60 °C |
Boiling point: | 393.1±25.0 °C(Predicted) |
Density | 1.050±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | soluble in Methanol |
form | powder to crystaline |
pka | 4.77±0.10(Predicted) |
color | White to Almost white |
BRN | 2050867 |
Description and Uses
Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xi |
WGK Germany | 3 |
F | 9-21 |
HS Code | 2922.50.5000 |
HazardClass | IRRITANT |