Home Categories Chemical Reagents 1-(tert-Butoxycarbonyl)-3-azetidinemethanol
A1430912

1-(tert-Butoxycarbonyl)-3-azetidinemethanol , 95% , 142253-56-3

CAS NO.:142253-56-3

Empirical Formula: C9H17NO3

Molecular Weight: 187.24

MDL number: MFCD06656141

Pack Size Price Stock Quantity
250MG RMB25.60 In Stock
500MG RMB28.00 In Stock
1G RMB31.20 In Stock
5G RMB118.40 In Stock
25G RMB479.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 55 °C
Boiling point: 268-273℃
Density  1.115
Flash point: 117°(243°F)
storage temp.  2-8°C
solubility  Soluble in Dimethyl sulfoxide (DMSO).
pka 14.82±0.10(Predicted)
form  powder to lump
color  White to Almost white
InChI InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3
InChIKey HXRDRJKAEYHOBB-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CC(CO)C1

Description and Uses

1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

It is an intermediate in organic syntheses

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-26-37-60
TSCA  No
HazardClass  IRRITANT
HS Code  29339900

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