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A1416350

LeukotrieneD4 , 97%,100ug/mLinethanol , 73836-78-9

Synonym(s):
LTD4

CAS NO.:73836-78-9

Empirical Formula: C25H40N2O6S

Molecular Weight: 496.66

MDL number: MFCD00036839

Pack Size Price Stock Quantity
25μg RMB2399.20 In Stock
50μg RMB4319.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 785.8±60.0 °C(Predicted)
Density  1.162±0.06 g/cm3(Predicted)
Flash point: 9℃
storage temp.  -70°C
solubility  A solution in ethanol
form  Liquid.
pka 3.03±0.10(Predicted)
color  Colorless to light yellow

Description and Uses

Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.

LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle.

Safety

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN 1230 3/PG 2
WGK Germany  3

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