LeukotrieneD4 , 97%,100ug/mLinethanol , 73836-78-9
Synonym(s):
LTD4
Pack Size | Price | Stock | Quantity |
25μg | RMB2399.20 | In Stock |
|
50μg | RMB4319.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 785.8±60.0 °C(Predicted) |
Density | 1.162±0.06 g/cm3(Predicted) |
Flash point: | 9℃ |
storage temp. | -70°C |
solubility | A solution in ethanol |
form | Liquid. |
pka | 3.03±0.10(Predicted) |
color | Colorless to light yellow |
Description and Uses
Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.
LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle.
Safety
Symbol(GHS) | GHS02,GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H225-H301+H311+H331-H370 |
Precautionary statements | P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
Hazard Codes | F,T |
Risk Statements | 11-23/24/25-39/23/24/25 |
Safety Statements | 7-16-36/37-45 |
RIDADR | UN 1230 3/PG 2 |
WGK Germany | 3 |