Pyocyanin , ≥98% , 85-66-5
Synonym(s):
5-Methyl-1(5H)-phenazinone;Pyocyanine;Sanasin;Sanazin
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB799.20 | In Stock |
|
| 25mg | RMB2640.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 133° |
| Boiling point: | 349.76°C (rough estimate) |
| Density | 1.1427 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | solid |
| pka | 2.42±0.20(Predicted) |
| color | Dark blue |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week. |
Description and Uses
Pyocyanine (85-66-5), a redox-active phenazine produced by?P. aeruginosa?and other pathogens, is an electron receptor, which stimulates redox cycling in bacteria as well as in a variety of human cell lines. It enhances oxidative metabolism, which increases the formation of intracellular reactive oxygen species (ROS) via reduction of NADPH. Pyocyanine accelerates neutrophil apoptosis?in vitro. Pyocyanine production by?P. aeruginosa?suppresses the acute inflammatory response by pathogen-driven acceleration of neutrophil apoptosis and associated reduction of local inflammation.
Pyocyanin is an antibiotic accelerator of neutrophil apoptosis.
