8-Bromoadenosine , 98% , 2946-39-6
Synonym(s):
6-Amino-8-bromopurine riboside;8-Bromoadenine-9-β-D -ribofuranoside
CAS NO.：2946-39-6
Empirical Formula: C10H12BrN5O4
Molecular Weight: 346.14
MDL number: MFCD00005733
EINECS: 220-959-0
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB74.40 | In Stock |
|
| 1G | RMB197.60 | In Stock |
|
| 5G | RMB758.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 210-212 °C (dec.)(lit.) |
| Boiling point: | 717.7±70.0 °C(Predicted) |
| Density | 1.8171 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | powder |
| pka | 12.89±0.70(Predicted) |
| color | white |
| Water Solubility | Soluble in DMSO, and DMF. Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 627737 |
| CAS DataBase Reference | 2946-39-6(CAS DataBase Reference) |
Description and Uses
8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.
8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22 |
| WGK Germany | 3 |
| F | 10-23 |
| HS Code | 2934 99 90 |
