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A1365150

Thiaminehydrochloride , 99% , 67-03-8

Synonym(s):
Thiamine hydrochloride;Thiamine chloride hydrochloride;Thiamine, Hydrochloride - CAS 67-03-8 - Calbiochem;Thiamio hydrochloridum;Vitamin B?

CAS NO.:67-03-8

Empirical Formula: C12H17N4OS.ClH.Cl

Molecular Weight: 337.27

MDL number: MFCD00012780

EINECS: 200-641-8

Pack Size Price Stock Quantity
25g RMB39.20 In Stock
100g RMB68.00 In Stock
250g RMB159.20 In Stock
500g RMB311.20 In Stock
2.5kg RMB1551.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 250 °C (dec.)(lit.)
Density  1.3766 (rough estimate)
refractive index  1.6000 (estimate)
FEMA  3322 | THIAMINE HYDROCHLORIDE
Flash point: 9°C
storage temp.  room temp
solubility  H2O: 0.1 g/mL at 20 °C, clear, colorless
pka pKa 4.8 (Uncertain);9.0 (Uncertain)
form  Crystalline Powder
color  White to almost white
PH 2.7-3.3
Odor sour mild bitter
Odor Type bland
Water Solubility  1 g/mL
Sensitive  Light Sensitive & Hygroscopic
Merck  14,9295
JECFA Number 1030
BRN  3851771
BCS Class 3
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents.
LogP -3.93
CAS DataBase Reference 67-03-8(CAS DataBase Reference)
EPA Substance Registry System Thiamine hydrochloride (67-03-8)

Description and Uses

Thiamine Hydrochloride is the hydrochloride salt form of thiamine (vitamin B1), a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Vitamin B1 helps prevent various health problems including heart damage.
Thiamine hydrochloride is used to prevent and treat thiamine deficiency states, which may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used for the treatment of Wernicke-Korsakoff syndrome, beriberi and thiamine deficiency related to chronic alcoholism. Thiamine hydrochloride is used as a food additive to add brothy/meaty flavor to gravies or soups. It is used also as a food supplement and flavoring ingredient with a bitter taste.

Thiamine is the water-soluble vitamin b1, required for normal digestion and functioning of nerve tissues and in the prevention of beriberi. It also acts as a coenzyme in the metabolism of carbohydrates. During processing, the higher and longer the heating period, the greater the loss. The loss is reduced in the presence of acid. Thiamine hydrochloride and thiamine mononitrate are two available forms. The mononitrate form is less hygroscopic and more stable than the hydrochloride form, making it suitable for use in beverage powders. It is used in enriched flour and is found as thiamine mononitrite in frozen egg substitute and crackers.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-39/23/24/25-23/24/25-11
Safety Statements  22-24/25-37/39-26-36-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
RTECS  XI7350000
3-8-10
TSCA  Yes
HS Code  29362200
Toxicity LD50 in mice (mg/kg): 89.2 i.v.; 8224 orally (Winter)

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