(-)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane , 97% , 93379-48-7

Synonym(s):
(−)-trans-α,α′-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol);(−)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-L-threitol;(4R,5R)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyldioxolane;1,1,4,4-Tetraphenyl-2,3-O-isopropylidene-L-threitol;TADDOL

CAS NO.：93379-48-7

Empirical Formula: C31H30O4

Molecular Weight: 466.58

MDL number: MFCD00064467

PRODUCT Properties

• Melting point: 193-195 °C(lit.)
• alpha: -65.5 º (c=1, CHCl3)
• Boiling point: 489.39°C (rough estimate)
• Density: 1.0864 (rough estimate)
• refractive index: -69 ° (C=1, CHCl3)
• storage temp.: Inert atmosphere,Room Temperature
• pka: 12.28±0.29(Predicted)
• form: Powder
• color: white
• optical activity: [α]19/D 62.6°, c = 1 in chloroform
• BRN: 3657855
• InChIKey: RNSJHECWLNVNFE-KYJUHHDHSA-N

Description and Uses

Hydrogen-bonding organocatalyst examined in terms of acidity, deprotonation enthalpies and hydrogen bonding

Catalyst involved in synthesis of cyclopropylamines via addition reactions of Grignard reagents to amides

Reactant or reagent involved in:

• Enantioswitching of catalytic asymmetric hydroboration
• Synthesis of derivative ligands for asymmetric hydroformylation of alkenes
• Amide-directed catalytic asymmetric hydroboration of trisubstituted alkenes
• Addition of deactivated alkyl Grignard reagents to aldehydes

Safety

• Hazard Codes: Xi,Xn
• Risk Statements: 36/38-36/37/38-20/21/22
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• HS Code: 29329970