A1315112
tert-Butyl isocyanate , 97% , 1609-86-5
Synonym(s):
2-isocyanato-2-methylpropane
CAS NO.:1609-86-5
Empirical Formula: C5H9NO
Molecular Weight: 99.13
MDL number: MFCD00002035
EINECS: 216-544-9
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 85.5°C |
Boiling point: | 85-86 °C(lit.) |
Density | 0.868 g/mL at 25 °C(lit.) |
vapor pressure | 79hPa at 20℃ |
refractive index | n |
Flash point: | 24 °F |
storage temp. | 2-8°C |
solubility | Chloroform (Soluble), DMSO (Slightly) |
form | Liquid |
color | Clear colorless |
Water Solubility | 1000g/L at 25℃ |
Sensitive | Moisture Sensitive |
BRN | 969479 |
Stability: | Hygroscopic, Moisture Sensitive |
LogP | 0.4 |
CAS DataBase Reference | 1609-86-5(CAS DataBase Reference) |
NIST Chemistry Reference | Propane, 2-isocyanato-2-methyl-(1609-86-5) |
EPA Substance Registry System | tert-Butyl isocyanate (1609-86-5) |
Description and Uses
t-Butyl Isocyanate is a useful intermediate in synthesizing SCH 503034, a potential drug in the treatment of Hepatitis C virus. The study discusses with data the drug inhibitive selectivity against the viral enzyme NS3 Protease.
Safety
Symbol(GHS) | GHS02,GHS05,GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H225-H302-H314-H317-H330-H334-H335 |
Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
Hazard Codes | F,T+,T |
Risk Statements | 11-14-22-26-34-37-42-36/37/38-23/24/25-10 |
Safety Statements | 16-26-36/37/39-45-43-30-7/9 |
RIDADR | UN 2484 6.1/PG 1 |
WGK Germany | 3 |
F | 10-21 |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | I |
HS Code | 29291090 |