(R)-4-Benzyl-2-oxazolidinone , 98% , 102029-44-7

CAS NO.：102029-44-7

Empirical Formula: C10H11NO2

Molecular Weight: 177.2

MDL number: MFCD00010846

EINECS: 600-264-2

PRODUCT Properties

• Melting point: 88-90 °C
• alpha: 62 º (C=1, CHCl3)
• Boiling point: 309.12°C (rough estimate)
• Density: 1.1607 (rough estimate)
• refractive index: 14.5 ° (C=5, MeOH)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly)
• form: Crystalline Powder
• pka: 12.78±0.40(Predicted)
• color: White to almost white
• optical activity: [α]18/D +64°, c = 1 in chloroform
• Water Solubility: Insoluble in water. Soluble in Chloroform.
• Sensitive: Hygroscopic
• BRN: 4782551

Description and Uses

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H320
• Precautionary statements: P264-P305+P351+P338+P337+P313
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• F: 3-10
• HS Code: 29349990