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A1240612

Berberine Chloride Hydrate , Analysis standard , 141433-60-5

Synonym(s):
Berberine;Berberine chloride form;Natural Yellow 18

CAS NO.:141433-60-5

Empirical Formula: C20H18ClNO4

Molecular Weight: 371.81

MDL number: MFCD00011939

EINECS: 211-195-9

Pack Size Price Stock Quantity
20MG RMB95.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 204-206 °C (dec.)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
Colour Index  75160
color  Pale Yellow to Yellow
Water Solubility  Soluble in water.
Sensitive  Light Sensitive
Merck  14,1154
BRN  3836585
Stability: Hygroscopic
InChIKey VKJGBAJNNALVAV-UHFFFAOYSA-M

Description and Uses

This alkaloid occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Primarily for the treatment of gastroenteritis, dysentery and other intestinal infections and conjunctivitis, purulent otitis media.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22
WGK Germany  2
RTECS  DR9866400
3-10
TSCA  Yes
HS Code  29399990

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