Home Categories Chemical Reagents N,O-Bis(trimethylsilyl)trifluoroacetamide
A1226512

N,O-Bis(trimethylsilyl)trifluoroacetamide , 96% , 25561-30-2

Synonym(s):
BSTFA;Bis(trimethylsilyl)trifluoroacetamide;BSTFA + TMCS;Silylating mixture V;N,O-Bis(trimethylsilyl)trifluoroacetamide

CAS NO.:25561-30-2

Empirical Formula: C8H18F3NOSi2

Molecular Weight: 257.4

MDL number: MFCD00008269

EINECS: 247-103-9

Pack Size Price Stock Quantity
5ML RMB24.00 In Stock
25ML RMB51.20 In Stock
100ML RMB158.40 In Stock
500ML RMB628.80 In Stock
2.5L RMB2512.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: -10°C
Boiling point: 45-50 °C14 mm Hg(lit.)
Density  0.97 g/mL(lit.)
refractive index  n20/D 1.384(lit.)
Flash point: 75 °C
storage temp.  2-8°C
solubility  Miscible with chloroform.
form  Liquid
pka 1.82±0.50(Predicted)
Specific Gravity 0.971
color  Colorless to pale yellow
Water Solubility  hydrolyses
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
Sensitive  Moisture Sensitive
BRN  3607620
Stability: Moisture Sensitive
InChIKey XCOBLONWWXQEBS-KPKJPENVSA-N
CAS DataBase Reference 25561-30-2(CAS DataBase Reference)
NIST Chemistry Reference Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)

Description and Uses

N,O-bis(trimethylsilyl)-trifluoroacetamide (BSTFA) is similar to BSA in specificity of modification and there are several studies which have used both reagents.One study found BSTFA superior to BSA in product stability and yield of derivative. Another study compared several trimethylsilyl donors for end-capping of silica and observed that BSTFA was more reactive than BSA but less reactive than TMCim. Both BSA and BSTFA were used to prepare trimethylsilyl derivatives of pyrimidines and purines.Current work has used BSTFA for metabolomics analysis of urine,for the measurement of khatamines (psychoactive amines of khat (Catha edulis Forsk), and for the measurement of acrylamide in cocoa.

Safety

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H225-H302-H314
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  C,F,T
Risk Statements  11-34-10-35-14
Safety Statements  26-36/37/39-45-16
RIDADR  UN 2924 3/PG 3
WGK Germany  3
10-21
Hazard Note  Flammable/Moisture Sensitive
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29310095

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