D-Biotin , ≥99%(HPLC), frozen dried powder , 58-85-5

Synonym(s):
Biotin;Vitamin B7;Vitamin H;D-(+)-Biotin;D(+)-Biotin

CAS NO.：58-85-5

Empirical Formula: C10H16N2O3S

Molecular Weight: 244.31

MDL number: MFCD00005541

EINECS: 200-399-3

PRODUCT Properties

• Melting point: 231-233 °C(lit.)
• Boiling point: 573.6±35.0 °C(Predicted)
• alpha: 89 º (c=1, 0.1N NaOH)
• Density: 1.2693 (rough estimate)
• refractive index: 90.5 ° (C=2, 0.1mol/L NaOH)
• storage temp.: -20°C
• solubility: H₂O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
• form: powder
• pka: 4.74±0.10(Predicted)
• color: White crystalline powder or fine long needles
• PH: 4.5 (0.1g/l, H2O)
• optical activity: [α]20/D +91±2°, c = 1% in 0.1 M NaOH
• Water Solubility: Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.
• Sensitive: Light Sensitive
• Merck: 14,1231
• BRN: 86838
• Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, formaldehyde, chloramine-T, nitrous acid.
• InChIKey: YBJHBAHKTGYVGT-ZKWXMUAHSA-N
• LogP: 0.861 (est)
• CAS DataBase Reference: 58-85-5(CAS DataBase Reference)
• NIST Chemistry Reference: Biotin(58-85-5)
• EPA Substance Registry System: Biotin (58-85-5)

Description and Uses

Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 1
• RTECS: XJ9088200
• F: 8
• TSCA: Yes
• HS Code: 29362930
• Hazardous Substances Data: 58-85-5(Hazardous Substances Data)
• Toxicity: LD50 orally in Rabbit: > 2000 mg/kg